Therapeutic mechanism of ginkgo biloba exocarp polysaccharides on gastric cancer
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چکیده
منابع مشابه
Reversal effect and mechanism of Ginkgo biloba exocarp extracts in multidrug resistance of mice S180 tumor cells
The aim of the present study was to investigate the reversal effect and its related mechanism of Ginkgo biloba exocarp extracts (GBEEs) in obtained multidrug resistance (MDR) of mice S180 tumor cells in vitro and in vivo. In order to simulate the clinical PFC [cis-dichlorodiamineplatinum, cisplatin (DDP) + fluorouracil (FU), FU+cyclophosphamide and cyclophosphamide] scheme, a gradually increasi...
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Ginkgo biloba has been used in traditional Chinese medicine for about 5000 years. A standardized preparation, EGb 761 has been recently prepared. The pharmacologically active constituents, flavonol glycosides and the terpene lactones are standardized. The terpene lactones comprise of ginkgolides A, B, C and bilobalides. The extract scavenges excess free radicals and pretreatment with EGb 761 re...
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Ginkgo biloba (EGb 761) as a phytotherapeutic agent used in otoneurology, psychiatry, and ophthalmology. We studied the efficacy of therapy with EGb 761 in 72 patients (44 male and 28 female) with chronic cochleovestibular disorders. We used pure-tone audiology, measuring pure-tone average, speech reception threshold, and speech discrimination score. Then we used craniocorpography to measure la...
متن کاملPolyphenols from Ginkgo biloba
By Sephadex LH-20 gel chromatography of an extract from Gingko biloba leaves, polymeric proanthocyanidins were eluted after the fractions of flavonol glycosides and biflavone glycosides. A purified proanthocyanidin polymer accounted for 86.6% of the total proanthocyanidins, and for 37.7% of the total antioxidant activity of this leaf extract. For structure elucidation, the polymer was submitted...
متن کاملGinkgo biloba extract induce cell apoptosis and G0/G1 cycle arrest in gastric cancer cells.
OBJECTIVE Previous studies have shown that the Ginkgo biloba extract (EGb761) can be used to anti-cancer. However, the mechanism by which EGb761 mediate this effect is still unclear. In the present study, EGb761 inhibited cell proliferation and induced cell apoptosis in gastric cancer cell was explored. METHODS The cell viability was detected by the CCK8 assay. The cell cycle and apoptosis wa...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2003
ISSN: 1007-9327
DOI: 10.3748/wjg.v9.i11.2424